Thursday, October 17, 2019

Marketing Management Essay Example | Topics and Well Written Essays - 250 words - 9

Marketing Management - Essay Example Despite its effectiveness, Warfarin monitoring is a major drawback, whereby blood is tested to determine international normalised ratio (INR) for proper dosage. This makes the process of administering the drug slow and thus its effect on an individual takes time. Research shows that increased intake of Warfarin causes a decrease in bone density, which eventually leads to osteoporoses. Pharmaceutical company Boehringer Ingelhiem have solved some of the problems caused by Warfarin with the introduction of Pradaxa. Mueller states, â€Å"Pradaxa is an oral drug that is unique in that it blocks the protein clotting thrombin† (Mueller, web). Its approval by US Food and Drug Administration (FDA) for prevention of stroke in patients with non-valvular atria fibrillation was also a major development. Pradaxa blood thinner does not require frequent monitoring for (INR) but offers good results in terms of efficacy. Though Pradaxa costs ten times more than Warfarin, the cost of monitoring required in Warfarin makes it more expensive than Pradaxa. One major disadvantage of Pradaxa is that its blood thinning effect cannot be reversed once administered unlike in Warfarin which is reversible. Since Pradaxa contains tartaric acid, it lowers the PH levels of Patients under it and in return leads to increased gastrointestinal bleeding. Approval of Xarelto by Bayer Company will be a further improvement of Warfarin and Pradaxa. Research shows that Xarelto does not need monitoring or dose adjustments, it can be used across all ages, and it is a non-inferior and has a superior efficacy. However there is increased bleeding in Xarelto

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